DR RAMAN KUMAR VERMA
PROFESSOR EMERITUS (RESEARCH)

Publications: 

1. Benzoxazolyl linked benzylidene based rhodanine and analogs as novel antidiabetic agents: synthesis, molecular docking, and in vitro studies Varinder Singh, Amanjot Singh, Gagandeep Singh, Raman K. Verma and Rajiv Mall Medicinal Chemistry Research. 2021, 30, 1905-1914.
2. Synthesis, Molecular docking, α-glucosidase inhibition, and antioxidant activity studies of novel benzimidazole derivatives, Gagandeep Singh, Amanjot Singh, Varinder Singh, Raman K. Verma, Jyoti Tomar and Rajiv Mall, Medicinal Chemistry Research. 2020, 29, 1846-1866.
3. Indolyl Linked meta-Substituted Benzylidenes as Novel Ligands: Synthesis, Biological Evaluation, and Molecular Docking Studies, Rajiv Mall, Amanjot Singh, Gagandeep Singh, Varinder Singh and Raman K. Verma, Journal of Heterocyclic Chemistry.  2019, 56, 1542-1555.
4. Novel indolyl linked para-substituted benzylidene-based phenyl containing thiazolidienediones and their analogs as α-glucosidase inhibitors: synthesis, in vitro and molecular docking studies, Jeewanjot Kaur, Amanjot Singh, Gagandeep Singh, Raman K. Verma and Rajiv Mall, Medicinal Chemistry Research. 2018, 27, 903-914.
5. Novel benzoxazole derivatives featuring rhodanine and analogs as antihypergycemic agents: synthesis, molecular docking, and biological studies, Varinder Singh, Amanjot Sing, Gagandeep Singh, Raman K. Verma and Rajiv Mall, Medicinal Chemistry Research. 2018, 27, 735-743.
6. Synthesis, biological evaluation and molecular docking studies of novel benzimidazole derivatives, Gagandeep Singh, Amanjot Singh, Raman K. Verma, Rajiv Mall and Uzma Azeem, Computational Biology and Chemistry. 2018, 72, 45–52.
7. Novel indole-2-carboxylic acid linked 3-phenyl-2-alkoxy propanoic acids: Synthesis, molecular docking and in vivo antidiabetic studies,  Amanjot Singh, Raman K. Verma, Anurag Kuhad and Rajiv Mall, Medicinal Chemistry Research. 2017, 26, 745-759.
8. Indolyl linked meta-substituted benzylidene-based novel PPAR ligands: Synthetic and docking studies, Raman K. Verma, Rajiv Mall and Amanjot Singh,  Medicinal Chemistry Research. 2015, 24, 1396-1407.
9. 3D-QSAR study of tyrosine and propanoic acid derivatives as pparα/γ dual agonists using CoMSIA, Raman K. Verma, Vijay Kumar, Prithwish Ghosh and Lalit K Wadhwa,  Medicinal Chemistry Research. 2013, 22, 287-302.
10. Design and synthesis of benzimidazole-linked meta-substituted benzylidenes/benzyls as biologically significant new chemical entities, Raman K. Verma, Rajiv Mall, Prithwish Ghosh, and Vijay Kumar,  Synthetic Communications. 2013,43, 1882–1895.
11. Design, synthesis and computational validation of novel benzimidazole/indole based PPARα and PPARγ partial agonists,  Raman K. Verma, Prithwish Ghosh, Vijay Kumar and Lalit K Wadhwa,  Journal of Chemical Sciences. 2013,125, 1555-1571. 
12. The application of Comparative Molecular Field Analysis for the design of α-anilino substituted-3-phenyl propanoic acids as novel PPARα/γ dual ligands, Raman K. Verma, Prithwish Ghosh, Vijay Kumar and Lalit K Wadhwa, Medicinal Chemistry Research. 2012, 21, 2873-2884.
13. Heterocyclyl linked anilines and benzaldehydes as precursors for biologically significant new chlmical entities,  Raman K. Verma, Vijay Kumar, Prithwish Ghosh and Lalit K Wadhwa, Journal of Chemical Sciences. 2012,124, 1063-1069.
14. A facile and new approach to biologically significant and functionalisable heterobiaryls, Raman K. Verma, Monika Aggarwal, Manisha Bansal and Inder Preet Kaur, Synthetic Communications. 2007,37,1-6.
15. A facile and new approach to synthesize 2-amino-4-(4-aminophenyl)-1h-1,3-diazol-1-yl-alkylaminomethanethiones, Raman K. Verma, Monika Aggarwal, Manisha Bansal and Inder Preet Kaur, Medicinal Chemistry Research. 2007,15,483-491.
16. A facile synthesis of 2-Benzyloxy/2-(4-isopropylbenzyloxy)-2-methyl-3-(4 substituted phenyl) propanoic acid based insulin sensitizing agents: RSR_13-15 and PKR_13-15, Raman K. Verma, Rubina Singla and V. T. Punniyakoti, Medicinal Chemistry Research. 2004, 13,660-676.
17. Calcium conjugates of amino acids as plant growth regulators, K. Verma, R. K. Sharma, V. L. Maheshwari and R. M. Kothari,  Journal of Plant Biology. 2000, 27, 85-88.
18. Synthesis of 2-substituted-[(2′-carboxybiphenyl-4-yl)methyl]benzimidzoles, Preet Mohinder Singh Bedi, Raman K. Verma and Manjeet Singh, Indian Journal of Chemistry. 1998, 37B, 801-803.
19. A facile and high yield route to succinanilic esters, Raman K. Verma,  Journal of Indian Chemical Society. 1992, 69, 683-684.
20. N-Aryl-α-chlorosuccinimide from maleanilic acids: Mechanistic and conformational studies, Raman K. Verma and Baldev Kumar,  Indian Journal of Chemistry. 1991, 30B, 822-824.
21. Esterification of maleanilic Acids: Intramolecular esterification through imidate ester, Baldev Kumar, Raman K. Verma and Harjit Singh, Indian Journal of Chemistry. 1986, 25B, 692-696.
22. Esterification at room temperature: A mixing affair only, Baldev Kumar and Raman K. Verma, Synthetic Communications. 1984, 14, 1359-1363.

ARTICLES

1. NMR-A Boon for the Organic Chemist, Raman K. Verma, IX Refresher Course in Chemistry, ACS and Dept. of Chemistry, Punjab University Chandigarh, Abstracts of lectures p46 (March-April 1994).
2. Hereditary Predisposition to Malignancies, Raman K. Verma, New Horizons in Human Biology, Editor I J S Bansal et al, 55-58 (1991), Today and Tomorrow Printers and Publishers, New Delhi-110 005.
3. ¹H NMR Spectra (52463M-52465M), IR Spectra (79495K-79497K), Baldev Kumar and Raman K. Verma, Biorad Sadtler Division. 1991, Philadelphia PA: Sadtler Research Laboratories.

A. INTERNATIONAL:

1. Esterification reactions of maleanilic acids: Synthetic and mechanistic approach, 10^th IUPAC International Conference on Organic Synthesis (ICOS -10), Indian Institute of Science, Bangalore (December 11-16, 1994)
2. A mixing affair package to useful derivatives of meleanilic acids at room temperature, 20^th  IUPAC Symposium on the chemistry of natural products, Chicago IL USA (September 15-20, 1996)
3. Facile synthesis of 2-substituted benzimidazole analogues of EXP 7711 angiotensin II receptor antagonists, 7^th Kyoto Conference of Organic Chemistry (IKCOC-7), Osaka Japan (November 10-14, 1997)
4. A Newer and efficient synthesis of 3-Aryl-2-Aryloxypropanoic acid based insulin sensitizing agents, International Symposium on the Drug Discovery Paradigm, Cambridge Health Tech Institute, USA and Astra Research Centre, Bangalore, Indian Institute of Science, Bangalore, India (September15-17, 1999)
5. International Symposium on Bioinformatics and Genomics, Confederations of Indian Industries, Karnataka Office, Indian Institute is Science, Bangalore, India (January15-17, 2001) -Attended
6. N-Alkyl-N’-(3,5-dibromo-4-hydroxy) benzylguanidine based centrally acting antihypertensive agents, International Symposium on Progress in Drug Discovery and Development Sciences, Astra Zeneca Research Foundation, Bangalore, India, Indian Institute of Science, Bangalore, India (January17-19, 2001)
7. Facile synthesis of suitably substituted 2-Aminoimidazoles and 2-Aminoimidazolines as expected antiasthmatic agents, 10^th Symposium on the Latest Trends in Organic Synthesis (LTOS -10), Gainesville, Florida, USA. (October 23-26, 2002)
8. A facile synthesis of 2-[(Substituted benzyl)imino/amino]imidazolidine/imidazoline based centrally acting antihypertensive agents, IUPAC International conference on Biodiversity and natural Products: Chemistry and Medical applications (ICOB-4 and ISCNP-24), Hotel Le Meridian, New Delhi, India (January 26-31, 2004)
9. Afacile synthesis of 2-Benzyloxy/2-(4-isopropylbenzyloxy)-2-methyl-3-(4-      substituted     phenyl) propanoic acid based insulin sensitizing agents: RSR_13-15 and PKR_13-15, 2^nd International Symposium, Current Trends In drug Discovery Research (CTDDR – 2004), CDRI, Lucknow, India (February 17-20, 2004)
10.  Design and synthesis of 4-(cyclicimido)-phenyl containing 2-amino-2-imidazoline and alkylguanidine based new and biologically significant ligands, International conference On Chemistry Biology Interface: synergistic New Frontiers (CBISNF 2004), Vigyan Bhavan, New Delhi, India (November 21-26, 2004)

Research Work in collaboration with Centre for Pharmacoinformatics (NIPER)

1. Ideal synthesis and comparative alignment studies of phenylpyridine and phenylpyridopyrimidine based compounds with expected antiasthmatic activity, Raman K. Verma*, M Elizabeth Sobhia^†, Monika Aggarwal, Manisha Bansal and Inder Preet Kaur, 3^nd International Symposium, Current Trends in Drug Discovery Research (CTDDR 2007), CDRI, Lucknow, India (February 17-21, 2007)
2. Synthesis and 3D QSAR studies of 2-Aminoimidazolines and their isosteres as central α₂ -adrenoceptor agonists, Raman K. Verma, M Elizabeth Sobhia^†, Manisha Bansal, Monika Aggarwal and Inder Preet Kaur, 3^nd International Symposium, Current Trends in Drug Discovery Research (CTDDR 2007), CDRI, Lucknow, India (February 17-21, 2007)
3. 3D QSAR studies on newly designed phenylpropanoic Acid based PPARγ agonists as potent insulin sensitizers, Raman K. Verma*, M Elizabeth Sobhia, Inder Preet Kaur, Manisha Bansal and Monika Aggarwal, 3^nd International Symposium, Current Trends in Drug Discovery Research (CTDDR 2007), CDRI, Lucknow, India (February 17-21, 2007)

B. NATIONAL:

1. Workshop on Pharmacoinformatics: Structure Based Drug Design, National Institute of Pharmaceutical Education and Research, SAS Nagar, Mohali, Punjab (March 13-15, 2008) – Attended
2. Workshop on Pharmacoinformatics: QSAR, National Institute of Pharmaceutical Education and Research, SAS Nagar, Mohali, Punjab (March 1-3, 2006) – Attended
3. Workshop on Pharmacoinformatics in Drug Design, National Institute of Pharmaceutical Education and Research, SAS Nagar, Mohali, Punjab (April14-16, 2005) – Attended
4. 3^rd National Symposium in Chemistry (NSC-3), Chemical Research Society of India (CRSI), Bangalore Sponsored, Department of Chemistry and Centre for Advanced Studies in    Chemistry, Panjab University, Chandigarh (February 2-4, 2001) – Attended
5. Summer School on Computer Aided Drug Design, National Institute of Pharmaceutical Education and Research, SAS Nagar, Mohali, Punjab (June 15-19, 1998) – Attended
6. Derivation of Maleanilic Acids: Synthetic, Mechanistic and Stereochemical Approach, 83^rd Indian Science Congress Punjabi University, Patiala (January 1996)
7. 5^th National Workshop on Mass Spectrometry, (5^th NWMS) ISMAS-BARC Bombay Sponsored RSIC, Punjab University, Chandigarh (April 19-26, 1994) – Attended
8. NMR Study of Some N-(o-and m-substituted) Aryl-α-chlorosuccinimides, National Seminar on Newer Methods of Synthesis in Chemistry, Punjabi University, Patiala (October 27-29, 1993)
9. Short Term Course on Instrumental Analysis. Chemical Engineering Division, TCRDC, Patiala (November 26-30, 1990) -Attended
10. Radiation and Chemical Mutagens, NCCYSRF, Punjabi University, Patiala (January 17-19, 1989)
11. NMR-A Diagnostic Aid: Present and Future Prospectives, UGC Seminar on Biotechnology, Punjabi University, Patiala (March 14-15, 1989)
12. Hereditary Predisposition to Malignancies, UGC Seminar on New Horizon in Human Biology, Punjabi University, Patiala, (November 9-10, 1989)

Field of Specialisation

• General and Advanced Organic Chemistry
• Organic Reaction Mechanisms
• Photochemistry and Pericyclic Reactions
• Organic Molecular Spectroscopy
• Organic Stereochemistry
• Organic Synthesis

Training programs conducted:

1. Coordinator, National Conference on Chemical and Environmental Sciences: Innovations and Advances – 2018 (CES: IA-2018), Department of Chemistry, Punjabi University, Patiala, February 15-16, 2018.
2. Organizing Secretary and Deputy Coordinator, One Day Seminar-Cum-Panel Discussion Punjabi University, Patiala: Drafting – IPR Policy – 2018, PUP: DIPRP – 2018, March 27, 2018
3. Convener, National Seminar on New Paradigm in Chemical Sciences: Synthetic and Analytical Perspectives – 2017 (NPICS: SAP – 2017), Department of Chemistry, Punjabi University, Patiala, February 9-10, 2017
4. Convener, National Seminar on New Paradigm in Chemical Sciences: Synthetic and Analytical Perspectives – 2016 (NPICS: SAP – 2016), Department of Chemistry, Punjabi University, Patiala, February 4-5, 2016
5. Organizing Secretary and Deputy Coordinator, One Day Seminar on General and Legal Aspects of Filing and Maintaining IPR-2016” (GLA: FMIPR – 2016), Intellectual Property Rights Cell (IPR – Cell), Punjabi University Patiala and PSCST-Chandigarh, March 29, 2016
6. Organizing Secretary and Deputy Coordinator, One Day Workshop on Prior Art Search and Filing of Patents (PSFP – 2015), Intellectual Property Rights Cell (IPR – Cell) Punjabi University Patiala and PSCST-Chandigarh, March 25, 2015
7. Convener, Synergistic Aspects of Chemical and Other Sciences -2015 (SACOS – 2015), Department of Chemistry, Punjabi University, Patiala, February 19-20, 2015
8. Coordinator, National Seminar on New Paradigm in Chemical Sciences (NPICS – 2014), Department of Chemistry, Punjabi University, Patiala, February 13, 2014
9. Coordinator, National Seminar on New Frontiers In Chemistry – 2013 (NFIC – 13), Department of Chemistry, Punjabi University, Patiala, February 15-16, 2013
10. Organizing Secretary and Deputy Coordinator, One Day Workshop on Practical Aspects on the Importance of Patents in Research (PAIPR – 2013), Intellectual Property Rights Cell (IPR – Cell), Punjabi University Patiala and PSCST-Chandigarh, February 12, 2013
11. Organizing Secretary, National Seminar on Chemistry an Interdisciplinary Science-2012 (NSCIS – 12), Department of Chemistry, Punjabi University, Patiala, February 15-16, 2012
12. Organizing Secretary, International Year of Chemistry-2011 (IYC – 11), Department of Chemistry, Punjabi University, Patiala, November 7, 2011
13. Organizing Secretary, National Seminar on Recent Advances in Chemistry and their impact on Emvironment-2011 (NSRACE – 11), Department of Chemistry, Punjabi University, Patiala, February 15-16, 2011
14. Chairperson, National Symposium on Emerging Trends in Chemistry -2010 (NSETC – 10), Department of Chemistry, Punjabi University, Patiala, February 15-16, 2010
15. Convener Technical Programme Committee, National Seminar on Emerging Trends in Chemistry – 2010 (NSET – 10), Department of Chemistry, Punjabi University, Patiala, February 15-16, 2010
16. Deputy Coordinator, Release of Information Brochure, Intellectual Property Rights Cell (IPR – Cell), Punjabi University Patiala and PSCST-Chandigarh, March 18, 2010
17. Oral Presentation, Post Genomic Era and Informatics: How the Revolution is Transforming Chemistry, Raman K. Verma, National Symposium on Emerging Trends in Chemistry – 2010 (NSETC 10), Department of Chemistry, Punjabi University, Patiala, February 15-16, 2010
18. Chairperson, 1^st Annual Conference on Recent Advances in Chemical and Environmental Sciences -2009 (RACES-09) Multani Mal Modi College, Patiala, January 15-16,2009
19. Invited Talk, NDDR: Rational Drug Design and Combinatorial Chemistry, Raman K. Verma, National Symposium on Recent Trends in Chemistry – 2009 (NSRTC – 09), Department of Chemistry, Punjabi University, Patiala, January 21-22, 2009
20. Chairperson, National Symposium on Recent Trends in Chemistry – 2009 (NSRTC – 09), Department of Chemistry, Punjabi University, Patiala, January 21-22, 2009
21. Convener Technical Programme Committee, National Symposium on Recent Trends in Chemistry – 2009 (NSRTC – 09), Department of Chemistry, Punjabi University, Patiala, January 21-22, 2009
22. Chairman, National Conference on Innovations in Drug Discovery and Research (NC-IDDR), Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, March 3-5, 2009

RESEARCH PROJECTS AND COLLABORATIONS:

HANDLED:

1. A Convenient Synthesis of β-Thioamido-α, β-Unsaturated Esters and Thioesters: Mechanistic and Biological Activity Studies, 1989-91 (MINOR: UGC NEW DELHI).
2. Photochemistry of Pesticides and Soil Treatment Agents on Solid Surfaces-Soils and Silica Gel: A Comparative Study, 1994-96 (MINOR: UGC NEW DELHI).
3. Substituted 4-Thiazolidinones and 2-Azetidinones: Synthetic and Biological Activity Studies, 1998-2000 (MINOR: UGC UNASSIGNED GRANT, PUNJABI UNIVERSITY, PATIALA).

COLLABORATED:

1. Synthesis of Super Plant Growth Regulators, Biotechnology Division, Thapar Corporate R & D Centre, Patiala
2. Application of Some Heteropoly Acid Salts as Catalysts in the Esterification Reactions, Department of Chemistry, Thapar Institute of Engineering and Technology, Patiala

ISLL-Punjabi University: Collaborative Research*

• Design Synthesis and Computational Validation of Medicinally Significant New Chemical Entities (NCEs)

* Punjabi University, Patiala and Ind-Swift Laboratories Ltd, Research and Development Centre, Mohali has signed general and confidentiality agreements to carry out collaborative research in areas of therapeutic significance on January 28, 2008.

OTHERS

1. Recipient of Punjabi University award for Improvement of Education research work in colleges, 1987-88.
2. Recipient of Punjabi University award for Improvement of Education research work in colleges, 1991-92.

 RESEARCH GUIDANCE:

• MPharm Guided:                 15
• MPhil Guided:                        5
• PhD Guided:                         10 (8 Supervised and 2 Co-supervised)

AWARDS:

ASSIGNMENTS AT PUNJABI UNIVERSITY: Till 31 December, 2018

• Member: ACD                                             
• Member: BPSAR
• Member: RAC
• Member: Faculty of Physical Sciences                                
• Member: Board of Post Graduate studies in Chemistry
• Member: Board of Under Graduate studies in Chemistry
• Member: Academic Council

• • Head: Department of Chemistry:01.07.2014 to 30.06.2017
  • Director: Institute for University Industry and Society Partnership: June, 2018 to December 2018
  • Coordinator: UGC: SAP(DRS-II): Till 30.06.2017
  • Deputy Coordinator: IPR-Cell: 2009 to 31.12.2018
  • Member: Internal Quality Assurance Cell (IQAC): 2010 to 31.12.2018
  • Member: Grievance Redressal Cell: 2018

ASSIGNMENTS AT OTHER UNIVERSITIES:

• Member: Board of Post Graduate studies in Chemistry: KUK
• Member: Board of Under Graduate studies in Chemistry: KUK
• Member: Board of Post Graduate studies in Chemistry: PU
• Member: Board of Post Graduate studies in Chemistry: MMU
• Member: Board of Post Graduate studies in Chemistry: RIMT
• Member: Board of Post Graduate studies in Chemistry: RIMT
• Member: Board of Management: Chitkara University Punjab
• Member: IQAC: Chitkara University Punjab
• Member: Editorial Board (Journal of Chemistry, Environmental Sciences and its Applications): Chitkara University, Punjab

MEMBERSHIP OF SOCIETIES: 

1. Indian Society for Mass Spectrometry, Life Membership No. of ISMAS: L – 358
2. American Chemical Society, Membership No. for year 2000: 2269533
3. Indian Society for Radiation and Photochemical Sciences, Life Membership No. of ISRAPS: L – 141

PATENTS PUBLISHED:

1. Novel indole derivatives as anti-diabetic agents and method thereof |Inventors: Raman K. Verma, Rajiv Mall and Amanjot Singh| Application No. 201611030034, dt. 09 March, 2018.
2. Novel benzimidazole derivatives as anti-diabetic agents and method thereof | Inventors: Raman K. Verma, Rajiv Mall and Amanjot Singh| Application No. 201611030905, dt. 30 March, 2018.

CURRENT POSITION

• Professor Emeritus (Research), Chitkara University, Punjab India since 8^th November 2021.

PREVIOUS POSITIONS:

M M Modi College, Patiala

Punjabi University, Patiala

Education Leadership, Research management

• 31 years (1987 – 2018) of teaching and 24 years (1997 – 2021) of research experience respectively.