Pharmaceutics Research Laboratory

The Department of Pharmaceutics is at the forefront of pharmaceutical education and research, blending academic excellence with state-of-the-art infrastructure. Our department is dedicated to the formulation, development, evaluation, and optimization of advanced drug delivery systems.

Infrastructure & Major Equipment

Our laboratories are equipped with cutting-edge instruments that support both academic instruction and high-impact research. These facilities provide hands-on training to students and enable innovative research across a range of pharmaceutics domains.

Sophisticated Instruments

This diverse range of sophisticated equipment empowers our researchers to carry out comprehensive pre-formulation, formulation, and characterization studies in the area of drug delivery and pharmaceutical technology.

Other Key Equipment’s in Pharmaceutics Lab

• Franze diffusion cells
• High Shear Homogeniser
• Probe Sonicator
• Double Compression Tablet Machine
• Disintegrator
• Rheometer

Research Excellence

The Department of Pharmaceutics is recognized for its dynamic research environment and consistent contributions to pharmaceutical science. Our faculty and research scholars actively publish in high-impact journals, participate in national and international conferences, and collaborate with industry partners for translational research.

Research Highlights

• Development of dosage forms using state of the art technology like 3D printing, microneedles and Spray drying.
• Development of novel drug delivery systems including nanoemulsions, transdermal patches, and microspheres.
• Formulation of biopharmaceuticals with enhanced bioavailability and targeted delivery.
• Work on microemulsions and nanotechnology-based platforms for wound healing and anti-infective therapies.
• Strong track record of funded projects and research grants.
• Continuous focus on innovation in formulation sciences aligned with global healthcare needs.
• We regularly organize industrial expert lectures and interactive sessions that foster innovation, industry alignment, and enhance placement opportunities for our students.
• Guided by a team of highly qualified and experienced faculty members who are dedicated to academic and research excellence.

Recent publications

• Kamal R, Singh TG, Bhatia R, Awasthi A. Formulation and evaluation of mesalamine-quercetin loaded self-nano emulsifying drug delivery systems (SNEDDS) for the management of colon cancer. BioNanoScience. 2025 Mar;15(1):1-5.
• Swami R, Popli P, Sal K, Challa RR, Vallamkonda B, Garg M, Dora CP. A review on biomacromolecular ligand-directed nanoparticles: New era in macrophage targeting. International Journal of Biological Macromolecules. 2025 Mar 7:141740.
• Pahwa R, Saini S, Sharma G, Panwar R, Tuli HS, Mishra N, Vishwas S, Singh TG, Gupta G, Dureja H, Singh SK. Lactoferrin-Conjugated Nanocarriers for Transformative Strategies in Cancer Management: New Insights on Breast Cancer Therapy. Current Drug Delivery. 2025 Mar 13.
• Rani A, Kaur R, Aldahish A, Vasudevan R, Balaji P, Dora CP, Chandrasekaran B, Singh TG, Sharma R. Nanostructured Lipid Carriers (NLC)-Based Topical Formulation of Hesperidin for Effective Treatment of Psoriasis. Pharmaceutics. 2025 Apr 7;17(4):478.
• Kamal R, Paul P, Mukherjee D, Singh TG, Bhatia R, Awasthi A. RP-HPLC Method Development for Simultaneous Determination of Mesalamine and Quercetin in Pure Forms and in Solid Lipid Nanoparticle Formulations. Separation Science Plus. 2025 Apr;8(4):e70042.
• Pant A, Sharma G, Saini S, Kaur G, Jain A, Thakur A, Singh B. QbD-driven development of phospholipid-embedded lipidic nanocarriers of raloxifene: extensive in vitro and in vivo evaluation studies. Drug Delivery and Translational Research. 2024 Mar;14(3):730-56.
• Swami R, Vij S, Sharma S. Unlocking the power of sugar: carbohydrate ligands as key players in nanotherapeutic-assisted targeted cancer therapy. Nanomedicine. 2024 Feb 1;19(5):431-53.
• Pant A, Singh G, Barnwal RP, Sharma T, Singh B. QbD-driven development and characterization of superparamagnetic iron oxide nanoparticles (SPIONS) of a bone-targeting peptide for early detection of osteoporosis. International Journal of Pharmaceutics. 2024 Apr 10;654:123936.
• Chakravarthy PS, Popli P, Challa RR, Vallamkonda B, Singh I, Swami R. Bile salts: unlocking the potential as bio-surfactant for enhanced drug absorption. Journal of Nanoparticle Research. 2024 Apr;26(4):76.
• Rohilla S, Awasthi R, Rohilla A, Singh SK, Chellappan DK, Dua K, Dureja H. Optimizing gefitinib nanoliposomes by Box-Behnken design and coating with chitosan: A sequential approach for enhanced drug delivery. ADMET and DMPK. 2024 Oct 19;12(4):657-77.
• Arora A, Sharma A, Singh S, Singh R, Singh A, Kakkar D, Sharma N. Nanoparticles encapsulated in Abelmoschus esculentus polysaccharide-based pellets as colon targeting approach. Journal of Microencapsulation. 2024 Oct 2;41(7):519-34.
• Vishwas S, Kumar R, Awasthi A, Corrie L, Bashir B, Khursheed R, Ramanunny AK, Gulati M, Singh TG, Gupta G, Dureja H. Formulation and optimization of fisetin nanoemulsion for the treatment of Alzheimer’s disease in rats: Pharmacokinetic and pharmacodynamic assessment. Journal of Drug Delivery Science and Technology. 2024 Nov 1;101:106269.
• Dora CP, Kushwah V, Yadav V, Kuche K, Jain S. Gemcitabine-phospholipid complex loaded lipid nanoparticles for improving drug loading, stability, and efficacy against pancreatic cancer. Molecular Pharmaceutics. 2024 May 15;21(6):2699-712.
• Khan MN, Dhakad PK, Sharma S, Sonawane G, Gilhotra RM. Formulation and evaluation of Amlodipine Besylate orodispersible tablet for the treatment of hypertension. Journal of Integrated Science and Technology. 2025;13(2):1036-.
• Kaur N, Popli P, Tiwary N, Swami R. Small molecules as cancer targeting ligands: Shifting the paradigm. Journal of Controlled Release. 2023 Mar 1;355:417-33.
• Goyal R, Raina D, Jaiswal V. Formulation and evaluation of antidepressants loaded with biopolymer for brain specificity. Materials Today: Proceedings. 2023 Mar 3.
• Ajmal G, Bonde GV, Mittal P, Pandey VK, Yadav N, Mishra B. PLGA/Gelatin-based electrospun nanofiber scaffold encapsulating antibacterial and antioxidant molecules for accelerated tissue regeneration. Materials Today Communications. 2023 Jun 1;35:105633.
• Shivaji Ashok Chakravarthy P, Grandhi S, Rajan S, Inderbir S. Optimization of quercetin loaded fast dissolving films by employing qbd as a designing tool for improved bioavailability. European Chemical Bulletin. 2023;12(5):69-80.
• Porwal O. Box-Behnken Design-based formulation optimization and characterization of spray dried rutin loaded nanosuspension: State of the art. South African Journal of Botany. 2022 Sep 1;149:807-15.
• Chopra H, Bibi S, Mohanta YK, Kumar Mohanta T, Kumar S, Singh I, Saad Khan M, Ranjan Rauta P, Alshammari A, Alharbi M, F. Alasmari A. In vitro and in Silico characterization of curcumin-loaded chitosan–PVA hydrogels: antimicrobial and potential wound healing activity. Gels. 2023 May 9;9(5):394.
• Abdullah Z, Ashraf MU, Barkat K, Badshah SF, Rehman U, Razzaq A, Mahmood A, Ulhaq F, Chopra H, Rashid S, Valko M. Formulation of pH-responsive highly swellable hydrogel scaffolds for controlled release of tramadol HCl: characterization and biocompatibility evaluation. Frontiers in Bioengineering and Biotechnology. 2023 May 26;11:1190322.
• Grewal S, Sharma T, Swami R. New era of nanoparticles facilitated co-delivery in cancer therapy: two heads are better than one. Journal of Nanoparticle Research. 2023 Sep;25(9):190.
• Kaur M, Nagpal M, Grewal AK, Chauhan S, Dora CP, Singh TG. Molecular Complex of HSIM-loaded Polymeric Nanoparticles: Potential Carriers in Osteoporosis. Current Drug Targets. 2023 Oct 1;24(13):1066-78.
• Malik R, Paudel KR, Manandhar B, De Rubis G, Shen J, Mujwar S, Singh TG, Singh SK, Gupta G, Adams J, MacLoughlin R. Agarwood oil nanoemulsion counteracts LPS-induced inflammation and oxidative stress in RAW264. 7 mouse macrophages. Pathology-Research and Practice. 2023 Nov 1;251:154895.
• Khalil MS, Shakeel M, Gulfam N, Ahmad SU, Aziz A, Ahmad J, Bibi S, Chopra H, Alhumaydhi FA, Idris AM, Khandaker MU. Fabrication of silver nanoparticles from ziziphus nummularia fruit extract: effect on hair growth rate and activity against selected bacterial and fungal strains. Journal of Nanomaterials. 2022;2022(1):3164951.
• Dhiman S, Bhatt S, Mannan A, Arora S, Singh TG. Formulation and characterization of zaleplon buccal disks using grafted Moringa oleifera gum. Journal of Applied Pharmaceutical Science. 2023 Jan 4;13(1):115-27.
• Thakur G, Singh A, Singh I. Formulation and evaluation of transdermal composite films of chitosan-montmorillonite for the delivery of curcumin. International journal of pharmaceutical investigation. 2016 Jan;6(1):23.
• Kalra S, Midha K, Kaur S. Purification of Quercetin by HPLC from green tea leaves and its application in cancer therapy. Indian Journal of Research in Pharmacy and Biotechnology. 2016 Mar 1;4(2):77.
• Juneja P, Kaur B, Odeku OA, Singh I. Development of Corn Starch-Neusilin UFL2 Conjugate as Tablet Superdisintegrant: Formulation and Evaluation of Fast Disintegrating Tablets. Journal of drug delivery. 2014;2014(1):827035.
• Kumar P, Singh I. Formulation and characterization of tramadol-loaded IPN microgels of alginate and gelatin: Optimization using response surface methodology. Acta pharmaceutica. 2010 Sep 1;60(3):295.
• Singh I, Kumar P, Kumar S, Rana V. Formulation and development of matrix tablets of tramadol using katira gum as release modifier. Yakugaku Zasshi. 2010 Sep 1;130(9):1225-31.

Recent Patents

• Liposomal formulations of sotorasib for targeted drug delivery and related methods, Thakur Gurjeet Singh, Chander Parkash, Sonia Dhiman, 202411094341, publication date: 03-01-2025
• Sublingual spray formulation for hypertension management and related methods, Thakur Gurjeet Singh, Akanksha Kumari, Loveleen Kaur, 202411094338, publication date: 03-01-2025
• Nanoparticle formulation for enhanced solubility and therapeutic efficacy of resveratrol and related methods Thakur Gurjeet Singh, Pankaj Popli, Rajan Swami, 202411094339, publication date: 03-01-2025
• Dry powder formulation of paclitaxel and related methods Thakur Gurjeet Singh, Rajan Swami, Sakshi Gaur, 202411094340, publication date: 03-01-2025
• Oral dosage form for sustained release of curcumin, Inderbir Singh, Garima Thakur,3011/del/2014, publication date: 27-05-2016, publication date: 03-01-2025
• An hplc method for the in-vitro quantification of gemcitabine Rajan Swami, Teenu Sharma, Pankaj Popli, Shashi Kant, Thakur Gurjeet Singh, 202411074079 , publication date: 11-10-2024
• Cinnarizine cocrystal loaded gastroretentive expandable filmspreparation and thereof, Inderbir Singh, Ritu Rathi, Arya Rai, Akshay Sharma, Harinderjit Singh Sidhu, 202411034451, publication date: 10-05-2024
• Biogenic nanoparticle and green synthesis thereof Atul Jain, Thakur Gurjeet Singh, Teenu Sharma, 202411018425, publication date: 12-04-2024
• Etoricoxib complex fast dissolving film Pooja Mittal, Somdutt Mujwar, Samrat Chauhan, Thakur Gurjeet Singh, 202211070370, publication date: 26-05-2023
• Solid dispersion of ursolic acid and method of manufacturing the same Pooja Mittal, Samrat Chauhan, Somdutt Mujwar, Thakur Gurjeet Singh, 202211070369, publication date: 26-05-2023
• Antimicrobial herbal food preservative composition Sushma Devi, Neeraj Mittal, Samrat Chauhan, Thakur Gurjeet Singh, 202311012133, publication date: 17-03-2023
• Adenosine conjugated docetaxel loaded solid lipid nanoparticles for targeted drug delivery, and a method for preparing the same Rajan Swami, Komal Sal, Indu Singh, Manish Kumar Jeengar, Thakur Gurjeet Singh, 202311064605, publication date: 13-10-2023
• Reserpine-loaded liposomal gel composition, and methods of preparation thereof, Nidhi Rani, Teenu Sharma, Rajan Swami, Thakur Gurjeet Singh, 202311064603, publication date: 13-10-2023
• Cinnarizine cocrystal loaded gastroretentive expandable films preparation and thereof, Inderbir Singh, Ritu Rathi, Arya Rai, Akshay Sharma, Harinderjit Singh Sidhu, 202411034451 publication date: 10-05-2024
• Formulation and evaluation of ursolic acid nanostructured lipid carriers for its anticancer potential, Pooja Mittal, Ramit Kapoor, Dileep Kumar, Samrat Chauhan, Somdutt Mujwar, Thakur Gurjeet Singh, Sanjana Mehta, 202411026896, Publication Date: 03-05-2024
• CEFIXIME NANOPARTICLES AND PREPARATION PROCESS THEREOF PALLAVI BASSI, THAKUR GURJEET SINGH, SUKHPREET SINGH, 202311002295, Publication Date: 13-01-2023

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