The present invention generally relates to a pharmaceutical composition of Non-SteroidalAnti-Inflammatory Drug (NSAID) suitable for topical delivery of drugs. Specifically, thepresent invention discloses an improved transdermal pharmaceutical composition comprisingof therapeutically effective amount of diclofenac or a pharmaceutically acceptable salt thereofand bio-enhancer, piperine or a metabolite, structural analogue or isomer thereof, preparationof the improved transdermal pharmaceutical composition and its use in the treatment ofinflammation and related pain.
Manju Nagpal, Balraj Saini, Thakur Gurjeet Singh, Geeta Aggarwal, Sandeep Arora, Harman Bakshi