The present invention relates to inhalable microparticles for systemic delivery. Specifically, the present invention relates to a formulation comprising inhalable microparticles of Hydroxychloroquine and surfactant. The present invention further relates to a process for preparing the formulation comprising inhalable microparticles of Hydroxychloroquine and surfactant based on quasi-emulsification solvent evaporation technique followed by freeze 10 drying. The present invention also provides a method for the management of Acute Respiratory Syndrome associated with COVID and viral morbidities comprising administering pharmaceutically effective amount of inhalable microparticles.
Sandeep Arora, Sukhbir Singh, Neelam Sharma