The present disclosure relates generally to pharmaceuticals. More specifically, thedisclosure is directed to a kneading method of preparing solid dispersioncompositions comprising insoluble drug Lafutidine along with amorphouspolymer- PVP-30 and emulsifying polymers- Poloxamer 407 and Gelucire 50/13.Said solid dispersion composition prepared by kneading method possesses high10 solubility in water in comparison to pure drug Lafutidine.
Sukhbir Singh, Sandeep Arora, Neelam Sharma, Supriya Kumari Singh, Neha Kanojia, Ajmer Singh Grewal