A KNEADING METHOD OF PREPARING A SOLID DISPERSION COMPOSITION OF LAFUTIDINE

The present disclosure relates generally to pharmaceuticals. More specifically, the disclosure is directed to a kneading method of preparing solid dispersion compositions comprising insoluble drug Lafutidine along with amorphous polymer- PVP-30 and emulsifying polymers- Poloxamer 407 and Gelucire 50/13. Said solid dispersion composition prepared by kneading method possesses high 10 solubility in water in comparison to pure drug – Lafutidine.

Inventors

SUKHBIR SINGH, SANDEEP ARORA, NEELAM SHARMA, SUPRIYA KUMARI SINGH, NEHA KANOJIA, AJMER SINGH GREWAL

Patent File Number - 202011053006         Patent File Date - 05/12/2020