A KNEADING METHOD OF PREPARING A SOLID DISPERSION COMPOSITION OF LAFUTIDINE

The present disclosure relates generally to pharmaceuticals. More specifically, thedisclosure is directed to a kneading method of preparing solid dispersioncompositions comprising insoluble drug Lafutidine along with amorphouspolymer- PVP-30 and emulsifying polymers- Poloxamer 407 and Gelucire 50/13.Said solid dispersion composition prepared by kneading method possesses high10 solubility in water in comparison to pure drug – Lafutidine.

Inventors Sukhbir Singh, Sandeep Arora, Neelam Sharma, Supriya Kumari Singh, Neha Kanojia, Ajmer Singh Grewal

Patent File Number - 202011053006        Patent File Date - 05-12-2020