Design of a low power Transimpedance amplifier (TIA) for analysis of structural behaviour of DNA through Nanopore sensors

Title: Design of a low power Transimpedance amplifier (TIA) for analysis of structural behavior of DNA through Nanopore sensors

Brief Description of project:

  • Nanopore are critical sensors, use to detect the small signal changes from a passing DNA strand through it and hence requires a highly sensitive low noise current to voltage amplifier for depicting the behavior of DNA.
  • Predicting an accurate model of nucleotide in DNA is of key interest for many genome studies.
  • A typical IA architecture consists of an integrator cascaded with a differentiator, along with pseudo-resistors buffer circuitry
  • The objective is to design a low power TIA architecture for depicting an accurate structural behavior of the DNA on the basis of changes in current observed by the nanopore sensor.

Principal Investigator:

• Dr. Rajnish Sharma
Team members:
• Kulbhushan Sharma, (PhD Scholar)
• AnishaPathania, (ME Scholar)
• ChanderPartap Singh, (ME Scholar)

Funding- INTERNAL        Project Start Date - 01/05/2018